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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
 

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Article DOI: 10.3791/63451-v • 08:40 min • January 20th, 2022
January 20th, 2022 •
1,2, 1,2, 1,2, 1,2
1INRAE, UR BIA, F-44316 Nantes, France, 2INRAE, BIBS Facility, F-44316 Nantes, France

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Ion mobility spectrometry (IMS) is an interesting complement to mass spectrometry for the characterization of biomolecules, notably because it is sensitive to isomerism. This protocol describes a tandem IMS (IMS/IMS) experiment, which allows the isolation of a molecule and the generation of the mobility profiles of its fragments.

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Cyclic Ion Mobility Spectrometer Tandem Ion Mobility Experiments Ion Mobility Profile Isomeric Structures Glycans Classification Structural Features Molecular Networks Mass Spectrometry Metabolites Drugs Of Interest Molecular Families Discrimination Between Structures Command Of Mass Spectrometry Ion Mobility Procedure Demonstration Simon Ollivier PhD Student Single-pass IMS Sequence Mobility Mode Cyclic Sequence Control Window Advanced Mode Add Bundle Single/Multipass
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