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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

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08:40 min

January 20, 2022

DOI:

08:40 min
January 20, 2022

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Summary

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Ion mobility spectrometry (IMS) is an interesting complement to mass spectrometry for the characterization of biomolecules, notably because it is sensitive to isomerism. This protocol describes a tandem IMS (IMS/IMS) experiment, which allows the isolation of a molecule and the generation of the mobility profiles of its fragments.

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