Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biochemistry / Characterizing Individual Protein Aggregates by…
JoVE Journal
Biochemistry

需要订阅 JoVE 才能查看此 内容. 登录或开始免费试用。

JoVE Journal Biochemistry
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
 

Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy

Article DOI: 10.3791/60108-v • 12:58 min • September 12th, 2019
September 12th, 2019 •
1, 1,2, 1, 1, 1,3
1Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, 2Institute of Biotechnology, Life Sciences Center, Vilnius University, 3Cavendish Laboratory, Department of Physics, University of Cambridge

章节

总结概括
Automatic Translation

We describe the application of infrared nanospectroscopy and high-resolution atomic force microscopy to visualize the process of protein self-assembly into oligomeric aggregates and amyloid fibrils, which is closely associated with the onset and development of a wide range of human neurodegenerative disorders.

Tags

Atomic Force Microscopy Infrared Nanospectroscopy Protein Aggregates Biomolecular Processes Morphological Resolution Chemical Resolution Structural Resolution Single Molecule Methods Protein Aggregation Human Disease Pharmacological Interventions Biomaterials Drug Delivery AFM Parameters High Resolution Imaging Fibrillar Aggregates
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter