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一种评价金黄色葡萄球菌感染先天免疫反应的小鼠模型
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JoVE 杂志 免疫与感染
A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
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一种评价金黄色葡萄球菌感染先天免疫反应的小鼠模型

10,140 Views

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09:15 min

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February 28, 2019

DOI:

10.3791/59015-v

DOI:
10.3791/59015-v

•

09:15 min
February 28, 2019

•

18 Views
, , , ,
1Department of Biomedical Engineering,University of California Davis, 2Department of Dermatology,Johns Hopkins University School of Medicine

Summary

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介绍了一种实时检测小鼠皮肤损伤和金黄色葡萄球菌感染的先天免疫反应的方法。通过将 lysm-egfp 小鼠 (具有荧光中性粒细胞) 与 lysm-egfp 杂交免疫缺陷小鼠株进行比较, 提高了对感染的认识, 并提出了对抗感染的方法。

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Cite this Article

Anderson, L. S., Reynolds, M. B., Rivara, K. R., Miller, L. S., Simon, S. I. A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection. J. Vis. Exp. (144), e59015, doi:10.3791/59015 (2019).

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