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A New Straightforward Method for Lipophilicity (logP) Measurement using 19F NMR Spectroscopy
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January 30, 2019
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A novel and straightforward variation of the shake-flask method was developed for accurate lipophilicity measurement of fluorinated compounds by 19F NMR spectroscopy.
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Wang, Z., Jeffries, B. F., Felstead, H. R., Wells, N. J., Chiarparin, E., Linclau, B. A New Straightforward Method for Lipophilicity (logP) Measurement using 19F NMR Spectroscopy. J. Vis. Exp. (143), e58567, doi:10.3791/58567 (2019).
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