需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0
9,718 Views
•
07:41 min
•
June 05, 2017
DOI:
1Center for Neuroscience,University of Pittsburgh, 2Department of Physical Medicine & Rehabilitation,University of Pittsburgh, School of Medicine, 3Safar Center for Resuscitation Research,University of Pittsburgh, 4Department of Biological Sciences, Mellon College of Science,Carnegie Mellon University
Summary
Automatically generated
Fast-scan cyclic voltammetry can monitor in vivo dopamine neurotransmission in the context of drugs, disease, and other experimental manipulations. This work describes the implementation of QNsim1.0, a software to model electrically stimulated dopamine responses according to the quantitative neurobiological model to quantify estimates of dopamine release and reuptake dynamics.
Read Article
Cite this Article
Harun, R., Grassi, C. M., Munoz, M. J., Wagner, A. K. Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0. J. Vis. Exp. (124), e55595, doi:10.3791/55595 (2017).
Copy