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Sonodynamische Therapie zur Behandlung des Glioblastoma multiforme im Mausmodell unter Verwendung eines tragbaren fokussierten Ultraschallsystems
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09:07 min
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February 10, 2023
DOI:
1Department of Neurosurgery,Johns Hopkins University School of Medicine, 2Department of Biomedical Engineering,Johns Hopkins University, 3Krieger School of Arts and Sciences,Johns Hopkins University, 4Department of Electrical Engineering and Computer Science,Johns Hopkins University, 5Department of Radiology, Cancer Imaging Division,Johns Hopkins University School of Medicine, 6Department of Mechanical Engineering,Johns Hopkins University, 7Department of Anesthesiology and Critical Care Medicine,Johns Hopkins University School of Medicine
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Hier beschreiben wir ein Protokoll, das detailliert beschreibt, wie die sonodynamische Therapie in einem in vivo Maus-Glioblastommodell mit Magnetresonanz-gesteuertem fokussiertem Ultraschall durchgeführt werden kann.
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Mess, G., Anderson, T., Kapoor, S., Thombre, R., Liang, R., Derin, E., Kempski-Leadingham, K. M., Yadav, S. K., Tyler, B., Manbachi, A. Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System. J. Vis. Exp. (192), e65114, doi:10.3791/65114 (2023).
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