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Journal / Bioengineering / Subdural Soft Electrocorticography (ECoG) Array…
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Bioengineering

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JoVE Journal Bioengineering
Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs
 

Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs

Article DOI: 10.3791/64997-v • 08:30 min • March 31st, 2023
March 31st, 2023 •
*1, *1, 1
1Laboratory for Soft Bioelectronic Interfaces, Neuro-X Institute, Ecole Polytechnique Fédérale de Lausanne
* These authors contributed equally

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Here, we present a method for the long-term performance and safety assessment of soft subdural electrode arrays in a minipig model, describing surgical method and tools, postoperative magnetic resonance imaging, electrophysiology of the auditory cortex, electrochemical properties of the implant, and postmortem immunochemistry.

Tags

Bioengineering Neurological Impairments Diseases Electrocorticography (ECoG) Arrays Drug-resistant Epilepsy Epileptic Region Resect Brain-computer Interfaces Epicortical Electrodes Movement Intention Robotic Limbs Paralyzed Patients Stiff Electrode Grids High-resolution Brain Recordings Long-term Biointegration Conformable Electrode Arrays Preclinical Studies Implant Technologies Functionality Safety Profile Translation To Human Patients Porcine Models Medical Devices Organ Sizes Easy Animal Handling Surgery Limitations
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