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Robust Tissue Fabrication for Long-Term Culture of iPSC-Derived Brain Organoids for Aging Research
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal Neuroscience
Robust Tissue Fabrication for Long-Term Culture of iPSC-Derived Brain Organoids for Aging Research

Robust Tissue Fabrication for Long-Term Culture of iPSC-Derived Brain Organoids for Aging Research

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08:20 min

May 12, 2023

DOI:

08:20 min
May 12, 2023

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Summary

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The present protocol provides a step-by-step procedure for the reproducible generation, maintenance, and aging of cerebral organoids derived from human-induced pluripotent stem cells (iPSCs). This method enables culturing and maturing cerebral organoids for extended periods, which facilitates the modeling of processes involved in brain aging and age-related pathogenesis.

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