Here we describe a new method to help elucidate the mechanisms of cellular immunity to Plasmodium during the blood stage of infection. This is an in vitro assay that measures infected red blood cell killing by cytotoxic lymphocytes.
de Lacerda, L., Castro, G., Gomes, C., Junqueira, C. In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes. J. Vis. Exp. (186), e63987, doi:10.3791/63987 (2022).