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Therapeutische evaluatie van fecale microbiotatransplantatie in een interleukine 10-deficiënt muismodel
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Immunology and Infection
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JoVE Journal Immunology and Infection
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
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Therapeutische evaluatie van fecale microbiotatransplantatie in een interleukine 10-deficiënt muismodel

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2,444 Views

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05:41 min

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April 06, 2022

DOI:

10.3791/63350-v

DOI:
10.3791/63350-v

•

05:41 min
April 06, 2022

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2 Views
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1Division of Gastroenterology, Department of Internal Medicine,University of Texas Medical Branch at Galveston, 2Department of Gastroenterology,Xiangya Hospital of Central South University

Summary

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De interactie van genetische gevoeligheid, mucosale immuniteit en intestinale micro-ecologische omgeving is betrokken bij de pathogenese van inflammatoire darmziekte (IBD). In deze studie pasten we fecale microbiota-transplantatie toe op IL-10-deficiënte muizen en onderzochten we de impact ervan op darmontsteking en hartfunctie.

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Xiao, Y., Zhong, X. S., Liu, X., Li, Q. Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model. J. Vis. Exp. (182), e63350, doi:10.3791/63350 (2022).

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