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Análisis multiplexado de la expresión génica de la retina y la accesibilidad a la cromatina utilizando scRNA-Seq y scATAC-Seq
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06:24 min
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March 12, 2021
DOI:
1Solomon H. Snyder Department of Neuroscience,Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science,The Johns Hopkins Hospital, 3Department of Ophthalmology,The Johns Hopkins Hospital, 4Department of Neurology,The Johns Hopkins Hospital, 5Institute for Cell Engineering,Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute,Johns Hopkins University School of Medicine
Summary
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Aquí, los autores muestran la utilidad de MULTI-seq para fenotipar y posteriormente emparejar scRNA-seq y scATAC-seq en la caracterización de los perfiles de accesibilidad transcriptómica y cromatina en la retina.
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Cite this Article
Weir, K., Leavey, P., Santiago, C., Blackshaw, S. Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq. J. Vis. Exp. (169), e62239, doi:10.3791/62239 (2021).
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