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肝癌的仿生模型，用于研究具有可调生物物理特性的3D环境中的肿瘤-斯特罗马相互作用
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
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肝癌的仿生模型，用于研究具有可调生物物理特性的3D环境中的肿瘤-斯特罗马相互作用

English

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5,825 Views

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08:40 min

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August 07, 2020

DOI:

10.3791/61606-v

DOI:
10.3791/61606-v

•

08:40 min
August 07, 2020

•

13 Views
, , , , ,
1Department of Medical Cell Biology,Uppsala University, 2Polymer Chemistry, Department of Chemistry-Ångström Laboratory,Uppsala University

Summary

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该协议提供了一个3D仿生模型与伴随的纤维频闪隔间。用生理上相关的水凝胶配制，比例模仿频闪细胞外基质的生物物理特性，是细胞相互作用、肿瘤生长和转移的活性介质。

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Cite this Article

Calitz, C., Pavlović, N., Rosenquist, J., Zagami, C., Samanta, A., Heindryckx, F. A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties. J. Vis. Exp. (162), e61606, doi:10.3791/61606 (2020).

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