/
/
A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
This content is Free Access.
A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
5,895 Views
•
08:40 min
•
August 07, 2020
DOI:
Summary
Automatically generated
This protocol presents a 3D biomimetic model with accompanying fibrotic stromal compartment. Prepared with physiologically relevant hydrogels in ratios mimicking the bio-physical properties of the stromal extracellular matrix, an active mediator of cellular interactions, tumor growth and metastasis.
Read Article
Cite this Article
Calitz, C., Pavlović, N., Rosenquist, J., Zagami, C., Samanta, A., Heindryckx, F. A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties. J. Vis. Exp. (162), e61606, doi:10.3791/61606 (2020).
Copy