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Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

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11:17 min

March 10, 2021

DOI:

11:17 min
March 10, 2021

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Summary

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The protocol describes experimental methods to obtain stable major histocompatibility complex (MHC) class I through potential β2-microglobulin (β2m) substitutions from different species. The structural comparison of MHC I stabilized by homologous and heterologous β2m were investigated.

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