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March 12, 2020
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Drosophila is a widely used experimental model suitable for screening drugs with potential applications for cancer therapy. Here, we describe the use of Drosophila variegated eye color phenotypes as a method for screening small-molecule compounds that promote heterochromatin formation.
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Zhang, L., Dao, K., Kang, A., Loyola, A. C., Shang, R., Li, J., Li, W. X. A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila. J. Vis. Exp. (157), e60917, doi:10.3791/60917 (2020).
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