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A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila
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Genetik
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JoVE Journal Genetik
A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila

A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila

DOI:
10.3791/60917-v

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06:22 min

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March 12, 2020

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, , , , , ,
1Tıp Fakültesi,University of California San Diego

Bölümler

  • 00:05Introduction
  • 01:29Heterochromatin-Promoting Drug Screening
  • 02:55Eye Color Change Scoring
  • 04:31Results: Representative Drug Screening in Drosophila
  • 05:33Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

Drosophila is a widely used experimental model suitable for screening drugs with potential applications for cancer therapy. Here, we describe the use of Drosophila variegated eye color phenotypes as a method for screening small-molecule compounds that promote heterochromatin formation.

Etiketler

DrosophilaHeterochromatinScreening MethodDrug IdentificationEye Color PhenotypeIn Vivo SystemHeterochromatin-promoting Compounds

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