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In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
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Immunology and Infection
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JoVE Journal Immunology and Infection
In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

English

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7,937 Views

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06:57 min

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February 20, 2020

DOI:

10.3791/60617-v

DOI:
10.3791/60617-v

•

06:57 min
February 20, 2020

•

12 Views
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1Department of Physiology, Institute of Bioscience,University of Sao Paulo

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Here, we present a compiled protocol to evaluate the cutaneous infection of mice with Leishmania amazonensis. This is a reliable method for studying parasite virulence, allowing a systemic view of the vertebrate host response to the infection.

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Aoki, J. I., Hong, A., Zampieri, R. A., Floeter-Winter, L. M., Laranjeira-Silva, M. F. In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice. J. Vis. Exp. (156), e60617, doi:10.3791/60617 (2020).

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