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Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice
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JoVE Journal Behavior
Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice

Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice

DOI:
10.3791/50470-v

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10:44 min

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July 05, 2013

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, , ,
1Lab of Immune and Neural Networks, Feinstein Institute for Medical Research,North Shore LIJ Health System, 2Department of Molecular Medicine,Hofstra North Shore LIJ School of Medicine

Chapters

  • 00:05Title
  • 01:36Tetrode Fabrication
  • 02:48Custom Microdrive Assembly
  • 05:38Tetrode VersaDrive Assembly
  • 07:25Gold-plating of Electrode Tips
  • 09:00Results: Representative Local Field Potentials and Single-unit Spike Waveforms
  • 10:09Conclusion

Summary

Automatic Translation

Automatic Translation

The design and assembly of microdrives for in vivo electrophysiological recordings of brain signals from the mouse is described. By attaching microelectrode bundles to sturdy driveable carriers, these techniques allow for long-term and stable neural recordings. The lightweight design allows for unrestricted behavioral performance by the animal following drive implantation.

Tags

Microdrive ArraysChronic Neural RecordingsAwake Behaving MiceTetrodesLocal Field PotentialsSingle-unit SignalsDorsal SubiculumElectrophysiological RecordingsNeural RecordingsMouse Brain

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