Journal
/
Immunology and Infection
/
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal Immunology and Infection
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform

Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform

English

Automatically Generated

8,783 Views

•

07:20 min

•

November 28, 2018

DOI:

10.3791/58643-v

DOI:
10.3791/58643-v

•

07:20 min
November 28, 2018

•

4 Views
, , , , , ,
1Centre for Misfolding Diseases, Department of Chemistry,University of Cambridge, 2European Research Institute for the Biology of Aging,University Medical Centre Groningen

Summary

Automatically generated

We describe protocols for using the wide field-of-view nematode tracking platform (WF-NTP), which enables high-throughput phenotypic characterization of large populations of Caenorhabditis elegans. These protocols can be used to characterize subtle behavioral changes in mutant strains or in response to pharmacological treatment in a highly scalable fashion.

Explore More Videos

C. ElegansAutomated Behavioral AnalysisDrug DiscoveryMisfolding DiseasesAgingGenetic ScreeningsParallel Worm TrackerImage Capture Software

Read Article

Cite this Article

Perni, M., Casford, S., Aprile, F. A., Nollen, E. A., Knowles, T. P., Vendruscolo, M., Dobson, C. M. Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform. J. Vis. Exp. (141), e58643, doi:10.3791/58643 (2018).

Download .ris file

Copy

Share Video

.

Copy