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自由行動ラットの脳波記録中に興奮性アミノ酸の透析

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

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自由行動ラットの脳波記録中に興奮性アミノ酸の透析

10,973 Views

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08:47 min

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November 08, 2018

DOI:

10.3791/58455-v

DOI:

10.3791/58455-v

•

08:47 min

November 08, 2018

•

7 Views

Marie Soukupová¹, Chiara Falcicchia¹, Francesca Lovisari¹, Selene Ingusci¹, Mario Barbieri¹, Silvia Zucchini¹, Michele Simonato¹

¹Department of Medical Sciences, Section of Pharmacology, Neuroscience Center,University of Ferrara and National Institute of Neuroscience

Summary

ここでは、腹側海馬脳波との組み合わせで、てんかんと非てんかんラットのアスパラギン酸とグルタミン酸のリリースを分析する体内マイクロダイアリシス法について述べる。アスパラギン酸とグルタミン酸の細胞外濃度は、病気のさまざまな段階と相関があります。

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