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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
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JoVE Journal Nörobilim
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

DOI:
10.3791/58455-v

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08:47 min

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November 08, 2018

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, , , , , ,
1Department of Medical Sciences, Section of Pharmacology, Neuroscience Center,University of Ferrara and National Institute of Neuroscience

Bölümler

  • 00:04Başlık
  • 00:42Epileptic Behavior Monitoring
  • 01:52Microdialysis Preparation
  • 03:54Microdialysis: Collection of Samples
  • 06:46Results: Extracellular Concentrations of Glutamate are Higher in Chronic Epileptic Rats
  • 07:34Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

Here, we describe a method for in vivo microdialysis to analyze aspartate and glutamate release in the ventral hippocampus of epileptic and non-epileptic rats, in combination with EEG recordings. Extracellular concentrations of aspartate and glutamate may be correlated with the different phases of the disease.

Etiketler

MicrodialysisExcitatory Amino AcidsEEGFreely Moving RatsNeurotransmitter ReleaseNeurological DiseasesFaraday CageEEG AmplifierEEG SoftwareEEG SignalTethered EEG Recording SystemAmplification FactorRinger’s SolutionFEP TubingGuide CannulaPlexiglass Cylinder

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