We describe the development of a lean PCOS-like mouse model with dihydrotestosterone pellet to study the pathophysiology of PCOS and the offspring from these PCOS-like dams.
Xue, P., Wang, Z., Fu, X., Wang, J., Punchhi, G., Wolfe, A., Wu, S. A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome. J. Vis. Exp. (140), e58379, doi:10.3791/58379 (2018).