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A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
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October 02, 2018
DOI:
1Department of Pediatrics,Johns Hopkins University School of Medicine, 2Department of Health,Beijing Military General Hospital, 3Southern Medical University, 4Department of Molecular and Cellular Physiology,Johns Hopkins University School of Medicine, 5Department of Gynecology and Obstetrics,Johns Hopkins University School of Medicine
Summary
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We describe the development of a lean PCOS-like mouse model with dihydrotestosterone pellet to study the pathophysiology of PCOS and the offspring from these PCOS-like dams.
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Xue, P., Wang, Z., Fu, X., Wang, J., Punchhi, G., Wolfe, A., Wu, S. A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome. J. Vis. Exp. (140), e58379, doi:10.3791/58379 (2018).
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