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Fabricação de anisotrópica poliméricas Artificial células apresentadoras para ativação de células T CD8 +
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Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

Fabricação de anisotrópica poliméricas Artificial células apresentadoras para ativação de células T CD8 +

português

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7,653 Views

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10:16 min

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October 12, 2018

DOI:

10.3791/58332-v

DOI:
10.3791/58332-v

•

10:16 min
October 12, 2018

•

1 Views
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1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology,Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy,Johns Hopkins University School of Medicine

Summary

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Aqui, apresentamos um protocolo para reproducibly e rapidamente gerar biologicamente inspirados, biodegradável articifical apresentadoras de células (aAPC) com tamanho ajustável, forma e apresentação de proteína de superfície de célula T expansão ex vivo ou in vivo .

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Cite this Article

Ben-Akiva, E., Rhodes, K. R., Meyer, R. A., Green, J. J. Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation. J. Vis. Exp. (140), e58332, doi:10.3791/58332 (2018).

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