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10:31 min
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October 25, 2018
DOI:
1Janssen R&D, 2Department of Microbiology and Immunology,University of North Carolina, 3UNC Food Allergy Initiative,University of North Carolina, 4Department of Pediatrics,University of North Carolina, 5Department of Chemistry,University of Alberta, 6Department of Molecular Medicine,Scripps Research Institute, 7Department of Medical Microbiology and Immunology,University of Alberta
Summary
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説明は、抗原のリポソーム化ナノ粒子と刺激的な B 細胞活性化の in vitroとin vivoでの使用の準備です。一貫性と堅牢な抗体は、ピーナッツ アレルギーの新しいモデルの開発につながった。抗原性リポソームの生成のためのプロトコルは、異なる抗原と免疫モデルに拡張できます。
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Bednar, K. J., Hardy, L., Smeekens, J., Raghuwanshi, D., Duan, S., Kulis, M. D., Macauley, M. S. Antigenic Liposomes for Generation of Disease-specific Antibodies. J. Vis. Exp. (140), e58285, doi:10.3791/58285 (2018).
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