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Immunology and Infection
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The Lambda Select cII Mutation Detection System
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Immunology and Infection
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JoVE Journal Immunology and Infection
The Lambda Select cII Mutation Detection System

The Lambda Select cII Mutation Detection System

English

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7,633 Views

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07:08 min

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April 26, 2018

DOI:

10.3791/57510-v

DOI:
10.3791/57510-v

•

07:08 min
April 26, 2018

•

1 Views
,
1Department of Preventive Medicine, USC Keck School of Medicine,University of Southern California

Summary

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We describe a detailed protocol for the Lambda Select cII mutation assay in cultured cells of transgenic rodents or the corresponding animals treated with a chemical/physical agent of interest. This approach has been widely used for mutagenicity testing of carcinogens in mammalian cells.

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Cite this Article

Besaratinia, A., Tommasi, S. The Lambda Select cII Mutation Detection System. J. Vis. Exp. (134), e57510, doi:10.3791/57510 (2018).

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