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Ved hjælp af menneskelige induceret pluripotente stamceller-afledt hepatocyt-lignende celler for Drug Discovery
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Chapters
- 00:04Title
- 01:05Culture of Human Induced Pluripotent Stem Cells
- 03:39Differentiation of Human iPSCs to Hepatocyte-like Cells and Small Molecule Screening
- 09:34Results: Differentiation of iPSCs and Identification of Small Molecules for Drug Discovery
- 11:12Conclusion
Protokollen præsenteres her beskriver en platform for at identificere små molekyler for behandlingen af leversygdom. En trinvis beskrivelse præsenteres beskriver hvordan at differentiere iPSCs i celler med hepatocyt egenskaber i 96-brønd plader og bruger cellerne til at screene for små molekyler med potentielle terapeutiske aktivitet.
