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Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis
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Developmental Biology
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JoVE Journal Developmental Biology
Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis

Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis

English

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7,995 Views

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09:51 min

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January 30, 2018

DOI:

10.3791/56499-v

DOI:
10.3791/56499-v

•

09:51 min
January 30, 2018

•

1 Views
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1UMR E-4320 TIRO-MATOs CEA/DRF/BIAM,Université Nice Sophia-Antipolis, 2UMR 7272 Institut de Chimie de Nice CNRS,Université Nice Sophia-Antipolis, 3CEA, Direction de la Recherche Fondamentale (DRF),Biosciences and Biotechnologies Institute (BIAM)

Summary

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Uranium is known to affect bone metabolism. Here, we present a protocol aimed at investigating the effect of natural uranium exposure on the viability, the differentiation, and the function of osteoclasts, the cells in charge of bone resorption.

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Gritsaenko, T., Pierrefite-Carle, V., Creff, G., Vidaud, C., Carle, G., Santucci-Darmanin, S. Methods for Analyzing the Impacts of Natural Uranium on In Vitro Osteoclastogenesis. J. Vis. Exp. (131), e56499, doi:10.3791/56499 (2018).

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