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Prostata-Krebs Zelle Modellgeneration des Widerstandes gegen die Anti-mitotische Agent Docetaxel
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
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Prostata-Krebs Zelle Modellgeneration des Widerstandes gegen die Anti-mitotische Agent Docetaxel

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12,833 Views

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06:44 min

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September 08, 2017

DOI:

10.3791/56327-v

DOI:
10.3791/56327-v

•

06:44 min
September 08, 2017

•

20 Views
, , , , ,
1Department of Pathology, Tisch Cancer Institute,Icahn School of Medicine at Mount Sinai, 2Department of Oncological Sciences, Tisch Cancer Institute,Icahn School of Medicine at Mount Sinai

Summary

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Widerstand gegen Krebs-Therapien trägt zum Fortschreiten der Erkrankung und Tod. Bestimmung der mechanistischen Grundlagen des Widerstands ist entscheidend für die Verbesserung der therapeutischen Antwort. Dieses Manuskript Details des Protokolls Taxan-resistente Zellmodelle von Prostatakrebs (PC) zu helfen, sezieren die Wege erzeugen Progression zu Docetaxel Widerstand bei PC Patienten beteiligt.

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Cite this Article

Mohr, L., Carceles-Cordon, M., Woo, J., Cordon-Cardo, C., Domingo-Domenech, J., Rodriguez-Bravo, V. Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel. J. Vis. Exp. (127), e56327, doi:10.3791/56327 (2017).

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