/
/
Modellering Hurtig-scanning cyklisk voltammetri data fra elektrostimulerede data om dopaminneurotransmission ved hjælp af QNsim1.0
A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Center for Neuroscience,University of Pittsburgh, 2Department of Physical Medicine & Rehabilitation,University of Pittsburgh, School of Medicine, 3Safar Center for Resuscitation Research,University of Pittsburgh, 4Department of Biological Sciences, Mellon College of Science,Carnegie Mellon University
Chapters
- 00:05Title
- 00:41Launching QNsim1.0 and Initialization of the Simulation Environment
- 03:01Using the Simulator Window
- 06:19Results: Simulations of Sample Data
- 07:04Conclusion
Hurtig-scanning cyklisk voltammetri kan overvåge in vivo dopamin neurotransmission i forbindelse med stoffer, sygdom og andre eksperimentelle manipulationer. Dette arbejde beskriver implementeringen af QNsim1.0, en software til modellering af elektrisk stimulerede dopaminresponser ifølge den kvantitative neurobiologiske model for at kvantificere estimater for dopaminfrigivelse og genoptagelsesdynamik.
