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WinCF-modellen - en billig og trekkbar mikrokosmos av en slimplugget bronchiole for å studere mikrobiologien av lungeinfeksjoner
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Immunology and Infection
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JoVE Journal Immunology and Infection
The WinCF Model – An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections

WinCF-modellen - en billig og trekkbar mikrokosmos av en slimplugget bronchiole for å studere mikrobiologien av lungeinfeksjoner

English

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8,956 Views

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06:57 min

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May 08, 2017

DOI:

10.3791/55532-v

DOI:
10.3791/55532-v

•

06:57 min
May 08, 2017

•

3 Views
, , , , , ,
1Skaggs School of Pharmacy and Pharmaceutical Sciences,University of California, San Diego, 2Department of Mechanical and Aerospace Engineering,University of California, San Diego

Summary

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Slimet koblet luftrom på cystisk fibrose (CF) pasienter som et ideelt miljø for mikrobiologiske patogener for å trives. Artikkelen beskriver en ny fremgangsmåte for å studere CF-lunge mikrobiomer i et miljø som etterligner hvor de forårsaker sykdommen og hvordan endring av de kjemiske betingelser kan kjøre mikrobielle dynamikk.

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Cite this Article

Comstock, W. J., Huh, E., Weekes, R., Watson, C., Xu, T., Dorrestein, P. C., Quinn, R. A. The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections. J. Vis. Exp. (123), e55532, doi:10.3791/55532 (2017).

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