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Zeitliche Reihenfolge der dynamischen Ausdruck von Daten aus Detaillierte Spatial Expression Maps
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February 09, 2017
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The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.
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Bailey, C. S., Bone, R. A., Murray, P. J., Dale, J. K. Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps. J. Vis. Exp. (120), e55127, doi:10.3791/55127 (2017).
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