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Temporal bestellen van Dynamic Expression gegevens van Uitgebreide Ruimtelijke Expression Maps
JoVE Journal
Developmental Biology
This content is Free Access.
JoVE Journal Developmental Biology
Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Temporal bestellen van Dynamic Expression gegevens van Uitgebreide Ruimtelijke Expression Maps

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11:52 min

February 09, 2017

DOI:

11:52 min
February 09, 2017

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Summary

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The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.

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