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Conception et utilisation d'un faible coût automatisé Morbidostat pour Adaptive Evolution des bactéries Sous Sélection des médicaments antibiotiques
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Genetics
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JoVE Journal Genetics
Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection
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Conception et utilisation d'un faible coût automatisé Morbidostat pour Adaptive Evolution des bactéries Sous Sélection des médicaments antibiotiques

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9,438 Views

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10:50 min

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September 27, 2016

DOI:

10.3791/54426-v

DOI:
10.3791/54426-v

•

10:50 min
September 27, 2016

•

3 Views
, , ,
1Electrical Engineering,National Tsing Hua University

Summary

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We describe a low cost, configurable morbidostat that enables the characterization of antibiotic drug resistance by dynamically adjusting the drug concentration. The device can be integrated with a multiplexed microfluidic platform. The approach can be scaled up for laboratory antibiotic drug resistance studies.

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Liu, P. C., Lee, Y. T., Wang, C. Y., Yang, Y. Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection. J. Vis. Exp. (115), e54426, doi:10.3791/54426 (2016).

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