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Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection
Kapitel
- 00:05Titel
- 00:46Assembly of the Morbidostat
- 04:13Pretesting and Running the Morbidostat
- 06:23On the Chip Growth Experiment
- 07:38Results: Evolution of Antibiotic Drug Resistance using a Morbidostat
- 09:31Conclusion
We describe a low cost, configurable morbidostat that enables the characterization of antibiotic drug resistance by dynamically adjusting the drug concentration. The device can be integrated with a multiplexed microfluidic platform. The approach can be scaled up for laboratory antibiotic drug resistance studies.
