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In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition
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Developmental Biology
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JoVE Journal Developmental Biology
In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition

In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition

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7,815 Views

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09:05 min

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August 20, 2016

DOI:

10.3791/54329-v

DOI:
10.3791/54329-v

•

09:05 min
August 20, 2016

•

4 Views
, , , , , ,
1Department of Ophthalmology,Far Eastern Memorial Hospital, 2Institute of Clinical Medicine,National Taiwan University, 3Department of Ophthalmology,National Taiwan University Hospital, 4College of Medicine,National Taiwan University

Summary

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A primary culture of bovine corneal endothelial cells was used to investigate the mechanism of corneal endothelial-mesenchymal transition. Furthermore, a rat corneal endothelium cryoinjury model was used to demonstrate corneal endothelial-mesenchymal transition in vivo.

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Ho, W., Su, C., Chang, J., Chang, S., Hu, F., Jou, T., Wang, I. In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition. J. Vis. Exp. (114), e54329, doi:10.3791/54329 (2016).

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