Journal
/
Developmental Biology
/
Adenovirale Gentherapie voor Diabetische keratopathie: Effecten op wondgenezing en Stem Cell Marker Expressie in Human Organ-gekweekte Corneas en Limbale epitheelcellen
JoVE Journal
Developmental Biology
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Developmental Biology
Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
Please note that all translations are automatically generated. Click here for the English version.

Adenovirale Gentherapie voor Diabetische keratopathie: Effecten op wondgenezing en Stem Cell Marker Expressie in Human Organ-gekweekte Corneas en Limbale epitheelcellen

Nederlands

Automatically Generated

9,010 Views

•

11:13 min

•

April 07, 2016

DOI:

10.3791/54058-v

DOI:
10.3791/54058-v

•

11:13 min
April 07, 2016

•

2 Views
, ,
1Eye Program, Board of Governors Regenerative Medicine Institute, Departments of Biomedical Sciences and Neurosurgery,Cedars-Sinai Medical Center, 2David Geffen School of Medicine,University of California, Los Angeles

Summary

Automatically generated

An example of adenoviral gene therapy in the human diabetic organ-cultured corneas is presented towards the normalization of delayed wound healing and markedly reduced epithelial stem cell marker expression in these corneas. It also describes the optimization of this process in stem cell-enriched limbal epithelial cultures.

Explore More Videos

Adenoviral Gene TherapyDiabetic KeratopathyWound HealingStem Cell Marker ExpressionHuman Organ-cultured CorneasLimbal Epithelial CellsEpithelial Wound HealingCorneal Stem Cell FunctionCorneal DiseasesStem Cell DysfunctionEpithelial DebridementCorneal HealingApoptotic Stromal Keratocytes

Read Article

Cite this Article

Kramerov, A. A., Saghizadeh, M., Ljubimov, A. V. Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells. J. Vis. Exp. (110), e54058, doi:10.3791/54058 (2016).

Download .ris file

Copy

Share Video

.

Copy