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March 23, 2016
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Here, we present a protocol to induce ocular hypertension in the murine eye that results in the loss of retinal ganglion cells as observed in glaucoma. Magnetic microbeads are injected into the anterior chamber and attracted to the iridocorneal angle using a magnet to block the outflow of aqueous humour.
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Ito, Y. A., Belforte, N., Cueva Vargas, J. L., Di Polo, A. A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice. J. Vis. Exp. (109), e53731, doi:10.3791/53731 (2016).
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