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A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
JoVE Revista
Medicina
This content is Free Access.
JoVE Revista Medicina
A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
DOI:

09:26 min

March 23, 2016

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Capítulos

  • 00:05Título
  • 01:02Preparation of Microneedle for Anterior Intracameral Injection
  • 02:13Induction of Ocular Hypertension
  • 06:51Results: Induction of Ocular Hypertension-Dependent Glaucoma Using the Magnetic Microbead Occlusion Model
  • 08:42Conclusion

Summary

Traducción Automática

Here, we present a protocol to induce ocular hypertension in the murine eye that results in the loss of retinal ganglion cells as observed in glaucoma. Magnetic microbeads are injected into the anterior chamber and attracted to the iridocorneal angle using a magnet to block the outflow of aqueous humour.

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