/
/
An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
A subscription to JoVE is required to view this content. Sign in or start your free trial.
8,791 Views
•
09:25 min
•
December 24, 2015
DOI:
Summary
Automatically generated
Adaptive immunity is controlled by dynamic 'immunological synapses' formed between T cells and antigen presenting cells. This protocol describes methods for investigating endothelial cells both as understudied physiologic APCs and as a novel type of 'planar cellular APC model'.
Read Article
Cite this Article
Martinelli, R., Carman, C. V. An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics. J. Vis. Exp. (106), e53288, doi:10.3791/53288 (2015).
Copy