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An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
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An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
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December 24, 2015
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Adaptive immunity is controlled by dynamic 'immunological synapses' formed between T cells and antigen presenting cells. This protocol describes methods for investigating endothelial cells both as understudied physiologic APCs and as a novel type of 'planar cellular APC model'.
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Martinelli, R., Carman, C. V. An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics. J. Vis. Exp. (106), e53288, doi:10.3791/53288 (2015).
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