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Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
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JoVE Journal Behavior
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice

Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice

DOI:
10.3791/53107-v

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10:28 min

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February 18, 2016

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, , ,
1Department of Psychiatry,Harvard Medical School, McLean Hospital

Chapters

  • 00:05Title
  • 00:52The Conditioned Place Preference (CPP) Boxes
  • 01:54CPP Testing: Pre-test (Day 1)
  • 04:09CPP Testing: Conditioning (Days 2-5)
  • 05:21Locomotor Sensitization: Preparations
  • 06:41Locomotor Sensitization: Testing
  • 08:13Results: Cocaine Treatments of C57B/L6N Mice Assayed by CPP and Locomotor Tests
  • 09:30Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol is intended to enable researchers to conduct experiments designed to test these aspects of addiction using the conditioned place preference and locomotor behavioral sensitization assays.

Tags

Keywords: CocaineBehavioral SensitizationConditioned Place PreferenceMiceDrug AddictionDrug-induced PlasticityHigh ThroughputCPP BoxesChambersNeutral ChamberPre-testDrug Pairing

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