/
/
Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
A subscription to JoVE is required to view this content. Sign in or start your free trial.
11,054 Views
•
07:43 min
•
May 12, 2015
DOI:
Summary
Automatically generated
We describe an immunohistochemistry protocol to study the profile of hippocampal neuron activation following exposure to a spatial learning task in a mouse model characterized by cognitive deficits of neurodevelopmental origin. This protocol can be applied to both genetic or pharmacological mouse models characterized by cognitive deficits.
Read Article
Cite this Article
Provenzano, G., Pangrazzi, L., Poli, A., Berardi, N., Bozzi, Y. Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders. J. Vis. Exp. (99), e52919, doi:10.3791/52919 (2015).
Copy