The malaria parasite invades and replicates within red blood cells. The accurate assessment of merozoite invasion and parasitemia is therefore crucial in assessing the course of malaria infection. Here we describe a flow cytometry based protocol for the measurement of these parameters in a mouse model of malaria.
Lelliott, P. M., McMorran, B. J., Foote, S. J., Burgio, G. In Vivo Assessment of Rodent Plasmodium Parasitemia and Merozoite Invasion by Flow Cytometry. J. Vis. Exp. (98), e52736, doi:10.3791/52736 (2015).