Journal
/
Immunology and Infection
/
الى الامام علم الوراثة شاشات طريق الضامة لتحديد<em> التوكسوبلازما</em> الجينات هامة الحصانة الذاتية للمقاومة إلى الإنترفيرون γ التي تعتمد على خلية
JoVE Journal
Immunology and Infection
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Immunology and Infection
Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
Please note that all translations are automatically generated. Click here for the English version.

الى الامام علم الوراثة شاشات طريق الضامة لتحديد<em> التوكسوبلازما</em> الجينات هامة الحصانة الذاتية للمقاومة إلى الإنترفيرون γ التي تعتمد على خلية

العربية

Automatically Generated

10,923 Views

•

11:21 min

•

March 12, 2015

DOI:

10.3791/52556-v

DOI:
10.3791/52556-v

•

11:21 min
March 12, 2015

•

2 Views
, , , , , , ,
1Department of Microbiology and Immunology,New York Medical College

Summary

Automatically generated

Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.

Explore More Videos

Toxoplasma GondiiMacrophagesForward Genetics ScreenIFN-γCell Autonomous ImmunityParasite MutantsParasite GenesChronic InfectionTachyzoiteBradyzoite

Read Article

Cite this Article

Walwyn, O., Skariah, S., Lynch, B., Kim, N., Ueda, Y., Vohora, N., Choe, J., Mordue, D. G. Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity. J. Vis. Exp. (97), e52556, doi:10.3791/52556 (2015).

Download .ris file

Copy

Share Video

.

Copy