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February 25, 2015
DOI:
1Department of Biomedical Engineering,Ohio State University Wexner Medical Center, 2Davis Heart & Lung Research Institute,Ohio State University Wexner Medical Center, 3The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory,Ohio State University Wexner Medical Center, 4Division of Cardiac Surgery, Department of Surgery,Ohio State University Wexner Medical Center, 5Departments of Pediatrics and Internal Medicine,Ohio State University, 6Advanced Lung Disease Program, Lung and Heart-Lung Transplant Programs,Nationwide Children’s Hospital, 7Division of Transplantation, Department of Surgery,Ohio State University Wexner Medical Center
Summary
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Ex-Vivo pulmonaire Perfusion (EVLP) a permis la transplantation pulmonaire chez l'homme pour devenir plus facilement accessible en permettant la capacité d'évaluer les organes et d'élargir le bassin de donneurs. Ici, nous décrivons l'élaboration d'un programme et des améliorations qui permettent un modèle reproductible pour l'expansion future EVLP de rat.
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Nelson, K., Bobba, C., Eren, E., Spata, T., Tadres, M., Hayes, Jr., D., Black, S. M., Ghadiali, S., Whitson, B. A. Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program. J. Vis. Exp. (96), e52309, doi:10.3791/52309 (2015).
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