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Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System
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Medicine
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JoVE Journal Medicine
Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System

Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System

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23,619 Views

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08:00 min

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November 17, 2014

DOI:

10.3791/52261-v

DOI:
10.3791/52261-v

•

08:00 min
November 17, 2014

•

21 Views
, , ,
1Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases,University of Louisville Medical School, 2Department of Microbiology and Immunology,University of Louisville Medical School

Summary

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Intubation-mediated intratracheal (IMIT) instillation of reagents is an excellent, noninvasive method for studying respiratory disease, as well as a method for instilling therapeutic reagents directly into the lung. It is a rapid and highly reproducible method which is suitable for preclinical testing.

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Lawrenz, M. B., Fodah, R. A., Gutierrez, M. G., Warawa, J. Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System. J. Vis. Exp. (93), e52261, doi:10.3791/52261 (2014).

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