La inducción de la proteína a través de Supresión<em> In Utero</em> La electroporación para definir Déficits en Neuronal migración en modelos transgénicos
La inducción de la proteína a través de Supresión<em> In Utero</em> La electroporación para definir Déficits en Neuronal migración en modelos transgénicos
Neuron migration is regulated by numerous cell autonomous and non-cell autonomous factors. This protocol shows how in utero electroporation can be used to determine whether a phenotype in a transgenic mouse is due to disruption of a cell intrinsic mechanism or impairment of interaction between the neuron and its environment.
Svoboda, D. S., Clark, A., Park, D. S., Slack, R. S. Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models. J. Vis. Exp. (95), e51983, doi:10.3791/51983 (2015).