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Inductie van Eiwit van de verwijdering door<em> In Utero</em> Electroporatie tekorten Definieer in neuronale migratie in transgene modellen
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models

Inductie van Eiwit van de verwijdering door<em> In Utero</em> Electroporatie tekorten Definieer in neuronale migratie in transgene modellen

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12:01 min

January 12, 2015

DOI:

12:01 min
January 12, 2015

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Summary

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Neuron migration is regulated by numerous cell autonomous and non-cell autonomous factors. This protocol shows how in utero electroporation can be used to determine whether a phenotype in a transgenic mouse is due to disruption of a cell intrinsic mechanism or impairment of interaction between the neuron and its environment.

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